cardiac arrhythmias — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8391	Cesium chloride	CsCl	Potassium Channel
	Cesium chloride (CsCl) is considered to be the most toxic of the alkali chlorides, inhibiting fungal growth.		Potassium Channel
T8183	Deslanoside	Desacetyllanatoside C,Deacetyllanatoside C	ATPase , Drug Metabolite
	Deslanoside (Desacetyllanatoside C) is a rapidly acting cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms. Deslanoside inhibits the Na-K-ATPase membrane p...		ATPase , Drug Metabolite
T20898	(R)-Propranolol hydrochloride	Dexpropranolol hydrochloride,(R)-(+)-Propranolol	Adrenergic Receptor
	(R)-Propranolol hydrochloride (Dexpropranolol hydrochloride) is the less active enantiomer of the anti-adrenoceptor (β-adrenoceptor) antagonist propranolol. Propranolol is a nonselective β-adrenergic receptor (βAR) antag...		Adrenergic Receptor
T15207	Eleclazine hydrochloride	GS 6615 hydrochloride	Sodium Channel
	Eleclazine hydrochloride (GS 6615 hydrochloride) is a novel inhibitor of late Na+ current (IC50: 0.7 uM).		Sodium Channel
T29050	UK 66914	UK66914,UK-66914	Potassium Channel
	UK 66914 is a K(+) channel blocker for the study of cardiac arrhythmias.		Potassium Channel
T28686	SB-237376 HCl	SB-237376 hydrochloride	Calcium Channel , Sodium Channel
	SB-237376 HCl (SB-237376 hydrochloride) is a calcium and potassium channel antagonist used in the treatment of cardiac arrhythmias.		Calcium Channel , Sodium Channel
T28686L	SB-237376		Calcium Channel , Sodium Channel
	SB-237376 is a calcium and potassium channel antagonist used to treat cardiac arrhythmias.		Calcium Channel , Sodium Channel
T27630	Isbogrel	CV4151,CV-4151,CV 4151	Prostaglandin Receptor
	Isbogrel (CV4151) is a small molecule thromboxane A2 synthase (TXA2 synthase) inhibitor that can be used to study cardiac arrhythmias, transient ischemic attacks and thrombosis.		Prostaglandin Receptor
T11239	Ethacizine hydrochloride	NIK-244,Ethacizin,NIK-244 hydrochloride	Sodium Channel
	Ethacizine hydrochloride (NIK-244) has antiarrhythmic activity, and its effects are related to cardiac activity and can be used to study arrhythmias and myocardial infarction.		Sodium Channel
T25701	Levosemotiadil	SD 3212,SA 3212	LDL , Calcium Channel
	Levosemotiadil（SA 3212） is a novel calcium antagonist and a very potent inhibitor of low-density lipoprotein oxidation.Levosemotiadil may be used to prevent lethal cardiac arrhythmias.		LDL , Calcium Channel
T23536	Xamoterol hemifumarate	ICI 118587 hemifumarate,Corwin hemifumarate	Adrenergic Receptor
	Xamoterol hemifumarate is a potent and selective β1-adrenoceptor agonist.Xamoterol hemifumarate is a potential compound for the study of the relationship between cardiac arrhythmias and β1-adrenergic stimulation with IKr...		Adrenergic Receptor
T77550	O-Desmethyl Quinidine		Others
	O-Desmethyl Quinidine is a novel quinidine analog with significant antiarrhythmic activity and low acute toxicity that may be useful in the treatment of cardiac arrhythmias.		Others
T68164	Tolamolol		Adrenergic Receptor
	Tolamolol is a selective β-adrenergic blocker that significantly reduces the degree of exercise-induced inhibition of the S-T segment and can be used in the treatment of cardiac arrhythmias.		Adrenergic Receptor
T1012	Acebutolol hydrochloride	Acebutolol HCl	Adrenergic Receptor
	Acebutolol hydrochloride (Acebutolol HCl) acts as a cardioselective beta-adrenergic antagonist with little effect on bronchial receptors and has intrinsic sympathomimetic properties. Acebutolol hydrochloride is the hydro...		Adrenergic Receptor
T2S2215	Crebanine		Apoptosis , Others , Akt
	1. Crebanine iv 5mg/kg can eonvert BaCl_2-induced arrhythmia into sinus rhythm in rats, and can significantly increase the tolerant dose of aconitine to produce ventrieular fibrillation(VF) and cardiac arrest (CA) in rat...		Apoptosis , Others , Akt
T19887	Teflurane	Abbott-16900,Tefluranum,Abbott 16900,Teflurano
	Teflurane is a halocarbon drug, Teflurane was investigated as an inhalational anesthetic, a high incidence of cardiac arrhythmias in patients, similarly to the cases of halopropane and norflurane.
T69472	Edrophonium
	Edrophonium is a rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
T63330	Clamikalant sodium
	Clamikalant sodium is a non-selective, ATP-sensitive potassium (KATP) channel blocker that can be used to study cardiac arrhythmias.
T26875	BN 50739	BN50739,BN-50739
	BN 50739 is an antagonist of platelet-activating factor (PAF). BN 50739 suppresses certain cardiac arrhythmias. PAF is released from ischaemic myocardium and may contribute to initiation of ischaemia-induced ventricular ...
T72323	Antiarrhythmic agent-1
	Antiarrhythmic agent-1 (example I), functioning as an antiarrhythmic agent and an IKr potassium channel blocker (IC 50 <1 μM), effectively inhibits cardiac arrhythmias.